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CA8 蛋白

CA8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713138
发货至: 中国
  • 抗原 See all CA8 蛋白
    CA8 (Carbonic Anhydrase VIII (CA8))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 2
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Carbonic anhydrase 8 protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product CA8 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    20 mM Tris-HCl, 500 mM NaCl, 1 mM DTT, pH 8.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CA8 (Carbonic Anhydrase VIII (CA8))
    别名
    Carbonic Anhydrase 8 (CA8 产品)
    别名
    AW546993 Protein, Ca8 Protein, Cals Protein, Cals1 Protein, Carp Protein, wdl Protein, zgc:110118 Protein, CA-VIII Protein, CALS Protein, CAMRQ3 Protein, CARP Protein, carbonic anhydrase 8 Protein, carbonic anhydrase VIII Protein, CAH8 Protein, Car8 Protein, ca8 Protein, CA8 Protein
    背景
    The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.
    分子量
    34 kDa
    NCBI登录号
    NP_004047
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