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CYP2A6 Protein (Myc-DYKDDDDK Tag)

CYP2A6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712760
发货至: 中国
  • 抗原 See all CYP2A6 蛋白
    CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    • 1
    HEK-293 Cells
    标记
    This CYP2A6 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CYP2A6 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CYP2A6 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
    别名
    Cyp2a6 (CYP2A6 产品)
    别名
    CPA6 Protein, CYP2A Protein, CYP2A3 Protein, CYPIIA6 Protein, P450C2A Protein, P450PB Protein, cyp2a6 Protein, cytochrome P450 family 2 subfamily A member 6 Protein, cytochrome P450 2A6 Protein, cytochrome P450 family 2 subfamily A member 6 L homeolog Protein, CYP2A6 Protein, cyp2a6.L Protein
    背景
    This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3 however, it has been renamed CYP2A6.
    分子量
    56.3 kDa
    NCBI登录号
    NP_000753
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