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COMT Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

COMT 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712474
发货至: 中国
  • 抗原 See all COMT 蛋白
    COMT (Catechol-O-Methyltransferase (COMT))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 9
    • 4
    • 4
    • 1
    • 1
    • 1
    资源
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This COMT protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human COMT (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COMT 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    COMT (Catechol-O-Methyltransferase (COMT))
    别名
    Comt (COMT 产品)
    别名
    Comt1 Protein, D16Wsu103e Protein, D330014B15Rik Protein, COMT Protein, mb-comt Protein, s-comt Protein, comt Protein, MGC154444 Protein, zgc:114157 Protein, si:dkey-13a21.15 Protein, zK13A21.15 Protein, zgc:162236 Protein, catechol-O-methyltransferase Protein, microRNA 4761 Protein, catechol-O-methyltransferase S homeolog Protein, methyltransferase Protein, catechol-o-methyltransferase Protein, catechol-O-methyltransferase a Protein, catechol-O-methyltransferase b Protein, catechol O-methyltransferase Protein, COMT Protein, Comt Protein, MIR4761 Protein, comt Protein, comt.2 Protein, comt.S Protein, Rv1703c Protein, Mb1729c Protein, comta Protein, comtb Protein, LOC100354142 Protein
    背景
    Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
    分子量
    29.9 kDa
    NCBI登录号
    NP_000745
    途径
    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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