LIM Domain Kinase 1 Protein (LIMK1) (Myc-DYKDDDDK Tag)
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- 抗原 See all LIM Domain Kinase 1 (LIMK1) 蛋白
- LIM Domain Kinase 1 (LIMK1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LIM Domain Kinase 1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human LIMK1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LIMK1 蛋白
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LIM Domain Kinase 1 (LIMK1) (AA 285-638) (Active) protein (GST tag)
LIMK1 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
LIM Domain Kinase 1 (LIMK1) (AA 1-647) protein (GST tag)LIMK1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
LIM Domain Kinase 1 (LIMK1) (AA 548-647) protein (GST tag)LIMK1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- LIM Domain Kinase 1 (LIMK1)
- 别名
- Limk1 (LIMK1 产品)
- 别名
- limk1 Protein, xlimk1 Protein, GB16654 Protein, LIMK1 Protein, LIMK Protein, LIMK-1 Protein, LIM domain kinase 1 Protein, LIM domain kinase 1a Protein, LIM domain kinase 1 L homeolog Protein, LIM-domain containing, protein kinase Protein, LIMK1 Protein, limk1a Protein, limk1 Protein, CpipJ_CPIJ000717 Protein, LOC413152 Protein, Limk1 Protein, limk1.L Protein
- 背景
- There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Feb 2011].
- 分子量
- 72.4 kDa
- NCBI登录号
- NP_002305
- 途径
- Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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