BPTF Protein (AA 2791-2911) (His tag,DYKDDDDK Tag)
BPTF
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Bind, ScA
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- 抗原 See all BPTF products
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2791-2911
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This BPTF protein is labelled with His tag,DYKDDDDK Tag.
- 应用范围
- Binding Studies (Bind), Screening Assay (ScA)
- 产品特性
- The peptide corresponding to amino acids 2791-2911 that contains the bromodomain sequences of BPTF / FALZ (accession number NP_872579.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.3 kDa.
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Bromodomain PHD Finger Transcription Factor (BPTF) (AA 2796-2907) protein (His tag)
BPTF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- 应用备注
- Recombinant BPTF / FALZ (2791-2911) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
- 限制
- 仅限研究用
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- 注意事项
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- 储存条件
- -80 °C
- 储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- 抗原
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
- 别名
- BPTF / FALZ (BPTF 产品)
- 别名
- FAC1 Protein, FALZ Protein, NURF301 Protein, 9430093H17Rik Protein, Falz Protein, BPTF Protein, bromodomain PHD finger transcription factor Protein, nucleosome-remodeling factor subunit NURF301 Protein, fetal alzheimer antigen, falz Protein, BPTF Protein, Bptf Protein, LOC5576547 Protein, CpipJ_CPIJ011285 Protein, bptf Protein
- 背景
- Bromodomain PHD finger transcription factor (BPTF), also known as Fetal Alzheimer antigen (FALZ), is a histone-binding component of NuRF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. BPTF protein contains a DNA-binding domain, a zinc finger motif and a bromodomain. Bromodomains recognize acetylated histone lysine residues and function as 'readers' of these epigenetic histone marks to regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. BPTF also specifically recognizes H3 tails trimethylated on lysine 4 (H3K4me3), which mark transcription start sites of virtually all active genes. It may also regulate transcription through direct binding to DNA or transcription factors.
- 分子量
- 20.3 kDa
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