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PRDM14 Protein (DYKDDDDK Tag)

PRDM14 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
产品编号 ABIN2669662
发货至: 中国
  • 抗原 See all PRDM14 蛋白
    PRDM14 (PR Domain Containing 14 (PRDM14))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 1
    • 1
    Baculovirus
    标记
    This PRDM14 protein is labelled with DYKDDDDK Tag.
    应用范围
    Enzyme Activity Assay (EAA), Screening Assay (ScA)
    产品特性
    Recombinant PRDM14 (accession number NP_078780.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 67 kDa.
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    Discover our top product PRDM14 蛋白
  • 应用备注
    Recombinant PRDM14 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
    限制
    仅限研究用
  • 注意事项
    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
    储存条件
    -80 °C
    储存方法
    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
  • 抗原
    PRDM14 (PR Domain Containing 14 (PRDM14))
    别名
    PRDM14 (PRDM14 产品)
    别名
    PFM11 Protein, PRDM14 Protein, prmd14 Protein, fc16b12 Protein, wu:fc16b12 Protein, PR/SET domain 14 Protein, PR domain containing 14 Protein, PRDM14 Protein, Prdm14 Protein, prdm14 Protein
    背景
    PRDM14 (PR Domain Containing 14) is a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. PRDM14 possesses histone methyltransferase activity. PRDM14 is a transcription factor that has both positive and negative roles on transcription. It is required for the maintenance of embryonic stem cell identity and the reacquisition of pluripotency in somatic cells. PRDM14 may play an essential role in germ cell development at two levels: the reacquisition of potential pluripotency, including Sox2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. PRDM14 directly up-regulates the expression of pluripotency gene Oct4 through its proximal enhancer. PRDM14 binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3.'
    分子量
    67 kDa
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