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PRMT7 Protein (DYKDDDDK Tag)

PRMT7 宿主: 人 宿主: Baculovirus Recombinant EAA, ScA
产品编号 ABIN2669660
发货至: 中国
  • 抗原 See all PRMT7 蛋白
    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
    蛋白类型
    Recombinant
    宿主
    • 4
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    • 1
    资源
    • 2
    • 2
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    Baculovirus
    标记
    This PRMT7 protein is labelled with DYKDDDDK Tag.
    应用范围
    Enzyme Activity Assay (EAA), Screening Assay (ScA)
    产品特性
    Recombinant PRMT7 (accession number NP_061896.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 80.1 kDa.
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    Discover our top product PRMT7 蛋白
  • 应用备注
    Recombinant PRMT7 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. Specific Activity: Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3). Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s.
    限制
    仅限研究用
  • 注意事项
    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
    储存条件
    -80 °C
    储存方法
    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
  • 抗原
    PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
    别名
    PRMT7 (PRMT7 产品)
    别名
    ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 Protein, ATPRMT7 Protein, DL4310W Protein, FCAALL.195 Protein, protein arginine methyltransferase 7 Protein, RGD1304869 Protein, 4933402B05Rik Protein, BC006705 Protein, zgc:66172 Protein, protein arginine methyltransferase 7 Protein, protein arginine methyltransferase 7 L homeolog Protein, protein arginine N-methyltransferase 7 Protein, Protein arginine N-methyltransferase 7 Protein, PRMT7 Protein, Prmt7 Protein, prmt7.L Protein, prmt7 Protein, prmt-7 Protein
    背景
    PRMT7 (Protein Arginine Methyltransferase 7) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT7 specifically mediates the symmetrical dimethylation of histone H4 at Arg3 to form H4R3me2s. PRMT7 plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruitment of DNA methyltransferases at these sites. PRMT7 may also play a role in embryonic stem cell (ESC) pluripotency. PRMT7 is also able to mediate arginine methylation of histone H2A and myelin basic protein (MBP) in vitro. However, the biological relevance of such results is unclear.
    分子量
    80.1 kDa
    途径
    Ribonucleoprotein Complex Subunit Organization
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