c-FOS Protein (full length) (His tag)
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- 抗原 See all c-FOS (c-Fos) 蛋白
- c-FOS (c-Fos) (c-Fos)
- 蛋白类型
- Recombinant
- 产品特性
- full length
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宿主
- 人
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资源
- Baculovirus
- 标记
- This c-FOS protein is labelled with His tag.
- 应用范围
- Protein Interaction (PI)
- 产品特性
- Recombinant c-Fos was expressed from full length (accession number NM 003131) with an amino terminal polyhistidine tag in a baculovirus system and purified by an affinity column in combination with FPLC chromatography. The purified recombinant protein is greater than 90 % homogeneous and contains no detectable protease, DNase and RNase activity.
- 纯化方法
- Purified by an affinity column in combination with FPLC chromatography.
- 纯度
- The purified recombinant protein is greater than 90 % homogeneous and contains no detectable protease, DNase and RNase activity.
- Top Product
- Discover our top product c-Fos 蛋白
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c-Fos (c-Fos) (AA 2-180) protein (His-IF2DI Tag)
c-Fos 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
c-Fos (c-Fos) (AA 1-380) protein (GST tag)c-Fos 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
c-Fos (c-Fos) (AA 1-100) protein (GST tag)c-Fos 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
c-Fos (c-Fos) (AA 1-380) protein (Strep Tag)Crystallography grade c-Fos 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
c-Fos (c-Fos) (AA 1-380) protein (Strep Tag)Crystallography grade c-Fos 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
c-Fos (c-Fos) protein (His tag)c-Fos 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Recombinant c-Fos is suitable for DNA and protein-protein interaction assays. 100 ng is sufficient for DNA-protein and protein-protein interaction studies. The molecular weight of the protein is ~50 kDa. The standard curve for TransAM® AP-1 c-Fos was generated using the range of 40-2.5 ng of protein. NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.
- 限制
- 仅限研究用
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- 浓度
- 0.5 μg/μL
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- 抗原
- c-FOS (c-Fos) (c-Fos)
- 别名
- C-Fos (c-Fos 产品)
- 别名
- AP-1 Protein, C-FOS Protein, p55 Protein, c-fos Protein, D12Rfj1 Protein, cFos Protein, cFOS Protein, fos Protein, Fos proto-oncogene, AP-1 transcription factor subunit Protein, FBJ osteosarcoma oncogene Protein, proto-oncogene c-Fos-like Protein, FOS Protein, Fos Protein, LOC101078177 Protein
- 背景
- C-Fos is one of the proteins that form the heteromeric AP-1 transcription factor complex. AP-1 proteins play a role in the expression of many genes involved in the regulation of cellular processes such as differentiation, proliferation and apoptosis. The transcription factor AP-1 is composed of a mixture of heterodimeric protein complexes derived from the Fos and Jun families, including c-Fos, FosB, Fra-1, c-Jun, JunB and JunD. c-Fos is a nuclear phosphoprotein that forms a tight but non-covalently linked complex with the Jun/AP-1 transcription factor. In the heterodimer, Fos and Jun/AP-1 basic regions each seem to interact with symmetrical DNA half sites. Upon TGF-β activation, c-Fos forms a multimeric SMAD3/SMAD4/Jun/Fos complex at the AP-1/SMAD-binding site to regulate TGF-β-mediated signaling. c-Fos has a critical function in regulating bone morphogenesis.
- 途径
- S100 Proteins
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