Antigen 85B 蛋白
宿主: Mycobacterium tuberculosis
宿主: 大肠杆菌（E. Coli）
Recombinant
>90 %
EDA, SDS
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- 抗原
- Antigen 85B
- 蛋白类型
- Recombinant
- 宿主
- Mycobacterium tuberculosis
- 资源
- 大肠杆菌（E. Coli）
- 应用范围
- Endotoxin Detection Assay (EDA), SDS-PAGE (SDS)
- 纯度
- >90 %
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- The protein should be reconstituted in apirogenic sterile water or 1X PBS
- 缓冲液
- 1 % glycerol
- 储存条件
- 4 °C
-
- 抗原
- Antigen 85B
- 背景
- The 30kD-secretory protein antigen 85B (Ag85B) is the most abundant protein exposed by Mycobacterium tuberculosis acting as a potent immunoprotective antigen. Ag85B induces a strong T-cell proliferation and the IFN- secretion in most healthy individuals exposed to M. tuberculosis, in BCG-vaccinated mice and humans. It has been shown that antibodies against Ag85B are more prevalent in active tuberculosis patients with decreased cellular immune response.
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