COMP Protein (His tag)
-
- 抗原 See all COMP 蛋白
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This COMP protein is labelled with His tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
-
Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells, when rhCOMP / Thrombospondin-5 immobilized at 1 μg/well. More than 45 % of ATDC-5 cell adhesion will be induced.
- 纯度
- >88 % as determined by SDS-PAGE.
- Top Product
- Discover our top product COMP 蛋白
-
-
- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
-
- 抗原
- COMP (Cartilage Oligomeric Matrix Protein (COMP))
- 别名
- TSP5 (COMP 产品)
- 别名
- COMP Protein, EDM1 Protein, EPD1 Protein, MED Protein, PSACH Protein, THBS5 Protein, TSP5 Protein, cartilage oligomeric matrix protein Protein, COMP Protein, sce3551 Protein, CJA_1292 Protein, Comp Protein
- 背景
- Cartilage oligomeric matrix protein (COMP) is also known as Thrombospondin-5 (TSP5), EDM1, EPD1, MED, PSACH, THBS5, which belongs to the thrombospondin family. COMP / TSP5 contains 4 EGF-like domains, 1 TSP C-terminal (TSPC) domain, 8 TSP type-3 repeats. Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. COMP may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. COMP can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Thrombospondin-5 could play a role in the pathogenesis of osteoarthritis. COMP is a marker of cartilage turnover.
- 分子量
- 82 kDa
- 基因ID
- 1311
- UniProt
- P49747
-