TFPI2 Protein (His tag)
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- 抗原 See all TFPI2 蛋白
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TFPI2 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
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Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca - RPKPVE - Nval - WRK (Dnp) - NH2. The IC50 value is < 2. 5 nM, as measured in 100μL reaction mixture containing 1. 25 ng trypsin, 10μM substrate, 50 mM Tris, 10 mM CaCl2, 0. 15M NaCl, 0. 05 % Brij-35, pH 7. 5.
- 纯度
- >95 % as determined by SDS-PAGE.
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- Discover our top product TFPI2 蛋白
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Tissue Factor Pathway Inhibitor 2 (TFPI2) protein (His tag)
TFPI2 宿主: 人 宿主: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. Func
Tissue Factor Pathway Inhibitor 2 (TFPI2) (AA 23-213) protein (His tag)TFPI2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tissue Factor Pathway Inhibitor 2 (TFPI2) (AA 1-235) protein (GST tag)TFPI2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- 抗原
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- 别名
- TFPI2 (TFPI2 产品)
- 别名
- MGC68843 Protein, TFPI2 Protein, MGC108301 Protein, si:ch211-262k23.2 Protein, tfpi2 Protein, PP5 Protein, REF1 Protein, TFPI-2 Protein, AV000670 Protein, PP5/TFPI-2 Protein, tissue factor pathway inhibitor 2 L homeolog Protein, tissue factor pathway inhibitor 2 Protein, tfpi2.L Protein, TFPI2 Protein, tfpi2 Protein, Tfpi2 Protein
- 背景
- Tissue Factor Pathway Inhibitor 2 (TFPI-2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF-1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI-2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis.
- 分子量
- 22.7 kDa
- 基因ID
- 7980
- NCBI登录号
- NP_006519
- UniProt
- P48307
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