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Neuropilin 1 Protein (NRP1) (His tag)

NRP1 宿主: 人 宿主: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN2566805
发货至: 中国
  • 抗原 See all Neuropilin 1 (NRP1) 蛋白
    Neuropilin 1 (NRP1)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 8
    • 5
    • 1
    资源
    • 12
    • 11
    • 4
    • 3
    • 1
    HEK-293 Cells
    标记
    This Neuropilin 1 protein is labelled with His tag.
    应用范围
    Western Blotting (WB), ELISA
    产品特性

    Measured by its ability to bind with recombinant human VEGF165 in a functional ELISA.

    纯度
    >92 % as determined by SDS-PAGE.
    Top Product
    Discover our top product NRP1 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    Neuropilin 1 (NRP1)
    别名
    Neuropilin 1 (NRP1 产品)
    别名
    NRP1 Protein, cd304 Protein, neuropilin Protein, np-1 Protein, npn-1 Protein, nrp Protein, nrp-1 Protein, vegf165r Protein, BDCA4 Protein, CD304 Protein, NP1 Protein, NRP Protein, VEGF165R Protein, C530029I03 Protein, NP-1 Protein, NPN-1 Protein, Npn1 Protein, Nrp Protein, neuropilin 1 Protein, neuropilin 1 L homeolog Protein, NRP1 Protein, nrp1 Protein, Nrp1 Protein, nrp1.L Protein
    背景
    Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
    分子量
    70.7 kDa
    基因ID
    8829
    UniProt
    O14786
    途径
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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