CSF3R Protein (His tag)
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- 抗原 See all CSF3R 蛋白
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CSF3R protein is labelled with His tag.
- 应用范围
- Western Blotting (WB)
- 产品特性
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Measured by its ability to inhibit the GCSF-induced proliferation of NFS-60 mouse myeloid cells. The ED50 for this effect is typically 0. 02-2 μg /mL in the presence of 0. 125 ng /mL of recombinant human GCSF.
Fusion tag: C-His Tag
- 纯度
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product CSF3R 蛋白
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Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-627) protein (His tag)
CSF3R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 26-626) protein (His tag)CSF3R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-621) protein (His tag)CSF3R 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) protein (Fc Tag)CSF3R 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-134) protein (GST tag)CSF3R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 651-836) protein (His tag)Crystallography grade CSF3R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 651-837) protein (His tag)Crystallography grade CSF3R 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-627) protein (His tag)Crystallography grade CSF3R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 26-626) protein (His tag)Crystallography grade CSF3R 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-836) protein (rho-1D4 tag)Crystallography grade CSF3R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- This recombinant protein can be used for WB. For research use only.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -80 °C,-20 °C
- 储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- 抗原
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
- 别名
- GCSFR (CSF3R 产品)
- 别名
- CD114 Protein, GCSFR Protein, Cd114 Protein, Csfgr Protein, G-CSF-R Protein, G-CSFR Protein, CSF3R Protein, gcsfr Protein, cd114 Protein, colony stimulating factor 3 receptor Protein, colony stimulating factor 3 receptor (granulocyte) Protein, colony stimulating factor 3 receptor L homeolog Protein, granulocyte colony-stimulating factor receptor Protein, CSF3R Protein, Csf3r Protein, csf3r Protein, csf3r.L Protein, LOC100433338 Protein
- 背景
- Granulocyte Colony Stimulating Factor Receptor (G-CSFR) is also known as Cluster of Differentiation 114 (CD114), CSF3R and GCSF, is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF), a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. G-CSFR belongs to a family of cytokine receptors known as the hematopoietin receptor family. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type I II (FNIII) domains in the extracellular region. G-CSFR is present mainly on precursor cells in the bone marrow, and, in response to stimulation by G-CSF, initiates cell proliferation and differentiation into mature neutrophilic granulocytes and macrophages. G-CSFR mediates the specific effect of GCSF through activating a variety of intracellular signaling cascades, including the Jak/Stat, PI3/Akt, Ras-Raf-MAP kinase, and Src family kinase pathways, and thus functions in defense against infection, inflammation and repair, and in the maintenance of steady state hematopoiesis. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. Mutations in the intracellular part of this receptor are also associated with certain types of leukemia.
- 分子量
- 69 kDa
- 基因ID
- 1441
- NCBI登录号
- NP_000751
- UniProt
- Q99062
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