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CEACAM6 Protein (His tag)

CEACAM6 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB Active
产品编号 ABIN2566459
发货至: 中国
  • 抗原 See all CEACAM6 蛋白
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 15
    • 1
    资源
    • 10
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This CEACAM6 protein is labelled with His tag.
    应用范围
    Western Blotting (WB)
    产品特性

    Measured by the ability of the immobilized protein to support the adhesion of calcium ionophore treated human neutrophils. When 200000 cells/well are added to CEACAM6 coated plates (10 μg/mL, 100μL/well), 45-70 % of the cells will adhere after 20 minutes at 37˚,C.

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CEACAM6 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))
    别名
    CEACAM 6 (CEACAM6 产品)
    别名
    CD66c Protein, CEAL Protein, NCA Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, carcinoembryonic antigen related cell adhesion molecule 6 Protein, Ceacam6 Protein, CEACAM6 Protein
    背景
    Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
    分子量
    32 kDa
    基因ID
    4680
    NCBI登录号
    NP_002474
    UniProt
    P40199
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