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NR1I3 Protein (His tag)

NR1I3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB Active
产品编号 ABIN2566333
发货至: 中国
  • 抗原 See all NR1I3 蛋白
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 5
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    资源
    • 5
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    HEK-293 Cells
    标记
    This NR1I3 protein is labelled with His tag.
    应用范围
    Western Blotting (WB)
    产品特性

    Measured by the ability of the immobilized protein to support the adhesion of mouse neutrophils. When 50000 cells/well are added to CXADR coated plates (4 μg/mL and 100μL/well ), approximately 20 % - 50 % will adhere specifically after 60 minutes at 37˚,C.

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product NR1I3 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    别名
    CAR (NR1I3 产品)
    别名
    AA209988 Protein, AI551208 Protein, CAR Protein, CAR-beta Protein, Care2 Protein, ESTM32 Protein, MB67 Protein, CAR1 Protein, CXR Protein, nuclear receptor subfamily 1 group I member 3 Protein, nuclear receptor subfamily 1, group I, member 3 Protein, NR1I3 Protein, Nr1i3 Protein
    背景
    Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V- type (D1) and a C2- type (D2) Ig-like domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.
    分子量
    24.9 kDa
    基因ID
    1525
    NCBI登录号
    NP_001329
    UniProt
    P78310
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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