Neurturin Protein (NRTN)
NRTN
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
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- 抗原 See all Neurturin (NRTN) 蛋白
- Neurturin (NRTN)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MARLGARPCG LRELEVRVSE LGLGYASDET VLFRYCAGAC EAAARVYDLG LRRLRQRRRL RRERVRAQPC CRPTAYEDEV SFLDAHSRYH TVHELSAREC ACV
- 产品特性
- Human Neurturin at a concentration of 100 ng/mL will support the survival of 65 % of newborn rat sympathetic neurons.
- 纯度
- < 98 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product NRTN 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing Neurturin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Neurturin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- Neurturin (NRTN)
- 别名
- Neurturin (NRTN 产品)
- 别名
- NRTN Protein, NTN Protein, neurturin Protein, NRTN Protein, Nrtn Protein
- 背景
- Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRalpha2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (206 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration.
- 基因ID
- 4902
- NCBI登录号
- NP_004549
- OMIM
- 4758826
- UniProt
- Q99748
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