LIN28A Protein (TAT tag)
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- 抗原 See all LIN28A 蛋白
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This LIN28A protein is labelled with TAT tag.
- 序列
- GPSVSNQQFA GGCAKAAEEA PEEAPEDAAR AADEPQLLHG AGICKWFNVR MGFGFLSMTA RAGVALDPPV DVFVHQSKLH MEGFRSLKEG EAVEFTFKKS AKGLESIRVT GPGGVFCIGS ERRPKGKSMQ KRRSKGDRCY NCGGLDHHAK ECKLPPQPKK CHFCQSISHM VASCPLKAQQ GP
- 产品特性
- Biological activity was measured by its ability to induce fluorescence in Lin28 reporter cells (293 cells transfected with fluorescent protein genes under Lin28 control). Optimum activity was achieved at 20 μg/mL after incubation for 72 hr.
- 纯度
- < 90 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product LIN28A 蛋白
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Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 3-182) protein (His tag)
LIN28A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 42-209) protein (His tag)LIN28A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) protein (GST tag)LIN28A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 2-209) protein (His tag)Crystallography grade LIN28A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 2-209) protein (His tag)Crystallography grade LIN28A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lin-28 Homolog A (C. Elegans) (LIN28A) protein (Myc-DYKDDDDK Tag)LIN28A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing Lin28-TAT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Lin28-TAT stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- 别名
- Lin28 (LIN28A 产品)
- 别名
- CSDD1 Protein, LIN-28 Protein, LIN28 Protein, ZCCHC1 Protein, lin-28A Protein, AL024421 Protein, ENSMUSG00000070700 Protein, Gm10299 Protein, Lin-28 Protein, Lin28 Protein, Tex17 Protein, csdd1 Protein, lin-28 Protein, lin28 Protein, zcchc1 Protein, sb:cb650 Protein, zgc:55584 Protein, RGD1566408 Protein, lin-28 homolog A Protein, lin-28 homolog A (C. elegans) Protein, lin-28 homolog A S homeolog Protein, LIN28A Protein, Lin28a Protein, lin28a.S Protein, lin28a Protein
- 背景
- Lin28 is a RNA-binding protein that belongs to a diverse family of structurally-related transcription factors. Lin28 is found abundantly in embryonic stem cells (ESCs), and to a lesser extent in placenta and testis. Lin28 has been shown to block let-7 microRNA processing and maturation, a necessary step in the differentiation of stem cells and certain cancer cell lines. Together with Sox2, Oct4, and Nanog, Lin28 can induce the reprogramming of primary human fibroblasts to a pluripotent state. Lin28 and other regulatory proteins can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing proteins into primary as well as transformed cells. Recombinant human Lin28-TAT is a 24.4 kDa protein containing 222 amino acid residues, including 13- residue C-terminal TAT peptide.
- 基因ID
- 79727
- NCBI登录号
- NP_078950
- OMIM
- 13375938
- UniProt
- Q9H9Z2
- 途径
- Stem Cell Maintenance
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