ITGA4 Protein (AA 131-275) (His tag)
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- 抗原 See all ITGA4 蛋白
- ITGA4 (Integrin alpha 4 (ITGA4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 131-275
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This ITGA4 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product ITGA4 蛋白
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Integrin alpha 4 (ITGA4) (AA 790-1032) protein (His-IF2DI Tag)
ITGA4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Integrin alpha 4 (ITGA4) (AA 98-207) protein (GST tag)ITGA4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Integrin alpha 4 (ITGA4) (AA 35-977) protein (His tag)Crystallography grade ITGA4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin alpha 4 (ITGA4) (AA 41-983) protein (His tag)Crystallography grade ITGA4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin alpha 4 (ITGA4) (AA 34-1032) protein (rho-1D4 tag)Crystallography grade ITGA4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin alpha 4 (ITGA4) (AA 41-1039) protein (rho-1D4 tag)Crystallography grade ITGA4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Integrin alpha 4 (ITGA4) protein (Myc-DYKDDDDK Tag)ITGA4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM Tris pH 7.5, 150 mM NaCl, 5 mM MgCl2
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- ITGA4 (Integrin alpha 4 (ITGA4))
- 别名
- Integrin alpha 4 (ITGA4 产品)
- 别名
- CD49D Protein, IA4 Protein, LOC100219853 Protein, integrin subunit alpha 4 Protein, integrin alpha 4 Protein, integrin subunit alpha 4 S homeolog Protein, ITGA4 Protein, Itga4 Protein, itga4.S Protein
- 背景
- The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains (reviewed in 1). Alpha 4 (?4) chain associates with either beta 1 (?1) or beta 7???7) chain. It has been demonstrated that the putative ligand-binding sites of both integrin ?4?1 and ?4?7 is located on the ?4 chain. These ligands included Madcam, VCAM, and fibronectin (2-4). Madcam is known as the principal ligand for integrin a4b7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin ?4?7, the gut mucosal homing receptor for peripheral T cells (5). This recombinant protein fragment includes the ligand and monoclonal antibody binding domains , this binding has been tested and verified in ELISA assays. This recombinant protein is recognized PSI antibodies Integrin 4? (IN1) (PSI 4827) and Integrin 4? (IN2) (PSI 4837), but not Integrin 4? (CT) (PSI 4783).
- 分子量
- 17 kDa (Calculated)
- 基因ID
- 3676
- NCBI登录号
- NP_000876
- OMIM
- 67191027
- UniProt
- P13612
- 途径
- Integrin Complex
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