IL1A 蛋白
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北京 101111
Quick Overview for IL1A 蛋白 (ABIN2468570)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
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产品特性
- The ED50 was determined by the dose - dependent proliferation of murine D10S cells is < 0.005 ng/mL, corresponding to a specific activity of > 2 x 108 units/mg.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing IL-1 alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-1 alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- IL-1 alpha
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背景
- IL-1beta is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1α is a 17.7 kDa protein containing 155 amino acid residues.
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基因ID
- 24493
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NCBI登录号
- NP_058715
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OMIM
- 8393593
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UniProt
- P16598
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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