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IL1A 蛋白

This Recombinant IL1A protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2468570
发货至: 中国

Quick Overview for IL1A 蛋白 (ABIN2468570)

抗原

See all IL1A 蛋白
IL1A (Interleukin 1 alpha (IL1A))

蛋白类型

Recombinant

生物活性

Active

宿主

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大鼠

资源

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大肠杆菌(E. Coli)

纯度

< 98 % by SDS-PAGE gel and HPLC analyses.
  • 序列

    MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS

    产品特性

    The ED50 was determined by the dose - dependent proliferation of murine D10S cells is < 0.005 ng/mL, corresponding to a specific activity of > 2 x 108 units/mg.

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing IL-1 alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-1 alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    IL1A (Interleukin 1 alpha (IL1A))

    别名

    IL-1 alpha

    背景

    IL-1beta is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1α is a 17.7 kDa protein containing 155 amino acid residues.

    基因ID

    24493

    NCBI登录号

    NP_058715

    OMIM

    8393593

    UniProt

    P16598

    途径

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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