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CLEC4G Protein (AA 55-293) (Fc Tag)

CLEC4G 宿主: 人 宿主: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE.
产品编号 ABIN2444087
发货至: 中国
  • 抗原 See all CLEC4G 蛋白
    CLEC4G (C-Type Lectin Domain Family 4, Member G (CLEC4G))
    蛋白类型
    Recombinant
    产品特性
    AA 55-293
    宿主
    • 2
    • 2
    资源
    • 2
    • 2
    HEK-293 Cells
    标记
    This CLEC4G protein is labelled with Fc Tag.
    序列
    AA 55-293
    产品特性
    This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.1 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >85 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC4G 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM Tris, 100 mM Glycine, pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -71 °C. Avoid repeated freeze-thaw cycles.
  • Yu, Huang, Chen, Liu, Wu, Pu, Wang, Kang, Zhou: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).

  • 抗原
    CLEC4G (C-Type Lectin Domain Family 4, Member G (CLEC4G))
    别名
    LSECtin (CLEC4G 产品)
    别名
    RGD1562320 Protein, DTTR431 Protein, LP2698 Protein, LSECtin Protein, UNQ431 Protein, 4930572L20Rik Protein, C-type lectin domain family 4 member G Protein, C-type lectin domain family 4, member G Protein, C-type lectin domain family 4, member g Protein, CLEC4G Protein, Clec4g Protein
    背景
    C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.
    分子量
    52.1 kDa
    NCBI登录号
    NP_940894
    UniProt
    Q6UXB4
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