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IL29 Protein (AA 20-200) (His tag)

IL29 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181309
发货至: 中国
  • 抗原 See all IL29 蛋白
    IL29 (Interleukin 29 (IL29))
    蛋白类型
    Recombinant
    产品特性
    AA 20-200
    宿主
    • 14
    • 1
    资源
    • 8
    • 4
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL29 protein is labelled with His tag.
    序列
    AA 20-200
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.1 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL29 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • 抗原
    IL29 (Interleukin 29 (IL29))
    别名
    IL-29 (IL29 产品)
    别名
    IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
    背景
    Interleukin-29, is a secreted protein which belongs to the IL-28 / IL-29 family, and is a type III interferon. It is also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, IFNλ1, IL-29 and IFNL1, and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL28A, IL28B, and IL29, also named interferonλ2 (IFNλ2), IFNλ3, and IFNλ1, respectively, are classII cytokine receptor ligands that are distantly related to members of the IL 10 family (11-13 % aa sequence identity) and the type I IFN family (15-19 % aa sequence identity). Human IL29 cDNA encodes a 200 amino acid (aa) residue precursor protein with a putative 19 aa signal peptide and a 181 aa mature protein, which is a monomer in solution. It shares 67 % and 69 % aa sequence identity with human IL28A and IL28B, respectively. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses and also may play a role in antiviral immunity. Interleukin-29 / IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
    分子量
    21.1 kDa
    NCBI登录号
    NP_742152
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