This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
CST4 Protein, Cst4 Protein, cystatin S Protein, CST4 Protein, Cyss Protein
背景
Cystatin-4 (CST4) is also known as Cystatin-S, Salivary acidic protein 1, which is a secreted protein, which belongs to the cystatin family. Cystatin-S is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in saliva, tears, urine and seminal fluid. Cystatin-4 / Cystatin S strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.