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POMC Protein (His tag)

POMC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2131235
发货至: 中国
  • 抗原 See all POMC 蛋白
    POMC (Proopiomelanocortin (POMC))
    蛋白类型
    Recombinant
    宿主
    • 5
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    资源
    • 11
    • 6
    • 2
    大肠杆菌(E. Coli)
    标记
    This POMC protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    27-267 amino acids: MGSSHHHHHH SSGLVPRGSH MWCLESSQCQ DLTTESNLLE CIRACKPDLS AETPMFPGNG DEQPLTENPR KYVMGHFRWD RFGRRNSSSS GSSGAGQKRE DVSAGEDCGP LPEGGPEPRS DGAKPGPREG KRSYSMEHFR WGKPVGKKRR PVKVYPNGAE DESAEAFPLE FKRELTGQRL REGDGPDGPA DDGAGAQADL EHSLLVAAEK KDEGPYRMEH FRWGSPPKDK RYGGFMTSEK SQTPLVTLFK NAIIKNAYKK GE
    产品特性
    Recombinant human POMC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
    纯度
    > 85 % pure
    Top Product
    Discover our top product POMC 蛋白
  • 应用备注
    POMC protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 1 mM DTT, 50 % glycerol and 0.2M NaCl.
    储存液
    Dithiothreitol (DTT)
    注意事项
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
  • 抗原
    POMC (Proopiomelanocortin (POMC))
    别名
    POMC (POMC 产品)
    别名
    MSH Protein, ACTH Protein, pomc Protein, SI:bZ36D5.1 Protein, SI:bZ36D5.4 Protein, si:bz36d5.2 Protein, BE Protein, Beta-LPH Protein, Clip Protein, Gamma-LPH Protein, Npp Protein, Pomc-1 Protein, Pomc1 Protein, alpha-MSH Protein, alphaMSH Protein, beta-MSH Protein, gamma-MSH Protein, CLIP Protein, LPH Protein, NPP Protein, POC Protein, Pomc2 Protein, proopiomelanocortin a Protein, pro-opiomelanocortin-alpha Protein, proopiomelanocortin Protein, pomca Protein, Pomc Protein, POMC Protein
    背景
    Pro-opiomelanocortin preproprotein, also known as POMC, a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. It regulates the corticosteroid production in the adrenal cortex. Also, POMC is cleaved into ten hormone chains named NPP, gamma-MSH, ACTH, alpha-MSH, CLIP, Lipotropin beta, Lipotropin gamma, Beta-MSH, Beta-endorphin and Met-enkephalin. Defects in the gene that encodes POMC are the cause of POMC deficiency, which is characterized by red hair and adrenal insufficiency.
    分子量
    28.9 kDa (262aa), confirmed by MALDI-TOF(molecular weight on SDS-PAGE will appear higher)
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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