FcRn Protein (AA 21-119, AA 24-290) (His tag)
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- 抗原 See all FcRn 蛋白
- FcRn (IgG receptor FcRn (FcRn))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-290, AA 21-119
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宿主
- 人
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资源
- 人细胞
- 标记
- This FcRn protein is labelled with His tag.
- 原理
- Recombinant Human FcRn & B2M Heterodimer (C-6His)
- 序列
- AESHLSLLYH LTAVSSPAPG TPAFWVSGWL GPQQYLSYNS LRGEAEPCGA WVWENQVSWY WEKETTDLRI KEKLFLEAFK ALGGKGPYTL QGLLGCELGP DNTSVPTAKF ALNGEEFMNF DLKQGTWGGD WPEALAISQR WQQQDKAANK ELTFLLFSCP HRLREHLERG RGNLEWKEPP SMRLKARPSS PGFSVLTCSA FSFYPPELQL RFLRNGLAAG TGQGDFGPNS DGSFHASSSL TVKSGDEHHY CCIVQHAGLA QPLRVELENL YFQGHHHHHH &IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
- 产品特性
- Recombinant Human FcRn is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala24-Leu290&Ile21-Met119) of Human FcRn, fused with a polyhistidine tag at alpha chain C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FcRn 蛋白
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IgG receptor FcRn (FcRn) (AA 24-297) protein (His tag)
FcRn 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IgG receptor FcRn (FcRn) (AA 22-297) protein (His tag)FcRn 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IgG receptor FcRn (FcRn) (AA 24-297) protein (His tag)FcRn 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IgG receptor FcRn (FcRn) (AA 51-160) protein (GST tag)FcRn 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
IgG receptor FcRn (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
IgG receptor FcRn (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag)FcRn 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
IgG receptor FcRn (FcRn) (AA 22-297) protein (His tag,Strep Tag)FcRn 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
IgG receptor FcRn (FcRn) (AA 24-297) (Active) protein (His tag,Strep Tag,AVI tag,Biotin)FcRn 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM HEPES,150 mM Nacl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FcRn (IgG receptor FcRn (FcRn))
- 别名
- FcRn (FcRn 产品)
- 别名
- FCRN Protein, alpha-chain Protein, FcRn Protein, Fc fragment of IgG receptor and transporter Protein, Fc receptor, IgG, alpha chain transporter Protein, FCGRT Protein, Fcgrt Protein
- 背景
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FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
Synonyms: IgG receptor FcRn,Neonatal Fc receptor,FCRN - 分子量
- 41.4 kDa
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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