PTPRN Protein (AA 687-979) (His tag)
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- 抗原 See all PTPRN 蛋白
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 687-979
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PTPRN protein is labelled with His tag.
- 原理
- Recombinant Human IA2/PTPRN (Met687-Gln979, N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MDISTGHMIL AYMEDHLRNR DRLAKEWQAL CAYQAEPNTC ATAQGEGNIK KNRHPDFLPY DHARIKLKVE SSPSRSDYIN ASPIIEHDPR MPAYIATQGP LSHTIADFWQ MVWESGCTVI VMLTPLVEDG VKQCDRYWPD EGASLYHVYE VNLVSEHIWC EDFLVRSFYL KNVQTQETRT LTQFHFLSWP AEGTPASTRP LLDFRRKVNK CYRGRSCPII VHCSDGAGRT GTYILIDMVL NRMAKGVKEI DIAATLEHVR DQRPGLVRSK DQFEFALTAV AEEVNAILKA LPQ
- 产品特性
- Recombinant Human Receptor-type tyrosine-protein phosphatase-like N is produced with our E. coli expression system. The target protein is expressed with sequence (Met687-Gln979) of Human PTPRN fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PTPRN 蛋白
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Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 693-979) protein (His tag)
PTPRN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 107-332) protein (His tag)PTPRN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (AA 205-311) protein (GST tag)PTPRN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- 别名
- Receptor-Type Tyrosine-Protein Phosphatase-Like N (PTPRN 产品)
- 别名
- IA-2 Protein, IA-2/PTP Protein, IA2 Protein, ICA512 Protein, R-PTP-N Protein, mIA-A Protein, mKIAA4064 Protein, Ia-2 Protein, fc43c04 Protein, ptprn Protein, wu:fc43c04 Protein, ia-2 Protein, ia2 Protein, ica512 Protein, r-ptp-n Protein, protein tyrosine phosphatase, receptor type N Protein, protein tyrosine phosphatase, receptor type, N Protein, protein tyrosine phosphatase, receptor type, Na Protein, protein tyrosine phosphatase, receptor type N L homeolog Protein, PTPRN Protein, Ptprn Protein, ptprna Protein, ptprn.L Protein
- 背景
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Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Synonyms: Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512 - 分子量
- 35.6 kDa
- UniProt
- Q16849
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