LCP2 Protein (AA 1-533) (His tag,T7 tag)
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- 抗原 See all LCP2 蛋白
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-533
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This LCP2 protein is labelled with His tag,T7 tag.
- 原理
- Recombinant Human Lymphocyte Cytosolic Protein 2/LCP2 (C-6His, N-T7 tag)
- 序列
- MASMTGGQQM GRGSMALRNV PFRSEVLGWD PDSLADYFKK LNYKDCEKAV KKYHIDGARF LNLTENDIQK FPKLRVPILS KLSQEINKNE ERRSIFTRKP QVPRFPEETE SHEEDNGGWS SFEEDDYESP NDDQDGEDDG DYESPNEEEE APVEDDADYE PPPSNDEEAL QNSILPAKPF PNSNSMYIDR PPSGKTPQQP PVPPQRPMAA LPPPPAGRNH SPLPPPQTNH EEPSRSRNHK TAKLPAPSID RSTKPPLDRS LAPFDREPFT LGKKPPFSDK PSIPAGRSLG EHLPKIQKPP LPPTTERHER SSPLPGKKPP VPKHGWGPDR RENDEDDVHQ RPLPQPALLP MSSNTFPSRS TKPSPMNPLP SSHMPGAFSE SNSSFPQSAS LPPYFSQGPS NRPPIRAEGR NFPLPLPNKP RPPSPAEEEN SLNEEWYVSY ITRPEAEAAL RKINQDGTFL VRDSSKKTTT NPYVLMVLYK DKVYNIQIRY QKESQVYLLG TGLRGKEDFL SVSDIIDYFR KMPLLLIDGK NRGSRYQCTL THAAGYPLEH HHHHH
- 产品特性
- Recombinant Human LCP2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro533) of Human LCP2 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LCP2 蛋白
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Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 1-533) protein (GST tag)
LCP2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 1-533) protein (Strep Tag)Crystallography grade LCP2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) (AA 1-533) protein (Strep Tag)Crystallography grade LCP2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) proteinLCP2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2) protein (Myc-DYKDDDDK Tag)LCP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,20 % glycerol, pH 8.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- LCP2 (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa) (LCP2))
- 别名
- Lymphocyte Cytosolic Protein 2/LCP2 (LCP2 产品)
- 别名
- AI323664 Protein, BB161688 Protein, SLP-76 Protein, SLP76 Protein, twm Protein, Slp76 Protein, lymphocyte cytosolic protein 2 Protein, Lcp2 Protein, LCP2 Protein
- 背景
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Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Synonyms: Lymphocyte cytosolic protein 2,SH2 domain-containing leukocyte protein of 76 kDa,SLP-76 tyrosine phosphoprotein,SLP76,LCP2 - 分子量
- 62.6 kDa
- UniProt
- Q13094
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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