UBE2C Protein (His tag)
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- 抗原 See all UBE2C 蛋白
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This UBE2C protein is labelled with His tag.
- 序列
- MHHHHHHAMG IRMASQNRDP AATSVAAARK GAEPSGGAAR GPVGKRLQQE LMTLMMSGDK GISAFPESDN LFKWVGTIHG AAGTVYEDLR YKLSLEFPSG YPYNAPTVKF LTPCYHPNVD TQGNICLDIL KEKWSALYDV RTILLSIQSL LGEPNIDSPL NTHAAELWKN PTAFKKYLQE TYSKQVTSQE P
- 纯度
- > 95 % by SDS-PAGE and HPLC analyses.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 1 EU/μg of rHuUBE2C, His as determined by LAL method.
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- Discover our top product UBE2C 蛋白
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Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (His tag)
UBE2C 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 1-179) protein (GST tag)UBE2C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 70-179) protein (GST tag)UBE2C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (AA 25-129) protein (GST tag)UBE2C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)UBE2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2C (UBE2C) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)UBE2C 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- 抗原
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- 别名
- UBE2C/UBCH10 (UBE2C 产品)
- 别名
- LOC458287 Protein, UBCH10 Protein, dJ447F3.2 Protein, 1110015A16Rik Protein, D2Ertd695e Protein, im:7137135 Protein, zgc:123190 Protein, ubiquitin conjugating enzyme E2 C Protein, ubiquitin-conjugating enzyme E2C Protein, ubiquitin conjugating enzyme E2 C L homeolog Protein, ubiquitin conjugating enzyme E2 C S homeolog Protein, UBE2C Protein, NAEGRDRAFT_82946 Protein, ube2c.L Protein, Ube2c Protein, ube2c.S Protein, ube2c Protein
- 背景
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Human Ubquitin Conjugating Enzyme E2 C (UBE2C)/UBCH10 is an essential mediator of mitotic destruction events and cell cycle progression. It catalyzes the destruction of cyclins A and B in conjunction with the anaphase-promoting complex, and therefore, plays an important role in the control of the cell exit from mitosis This activity is essential at then end of mitosis for the inactivation of their partner kinase Cdc2 and exit from mitosis into G1 of the next cell cycle. In addition, UBCH10 bears homology to yeast PAS2, a gene that is essential for biogenesis of peroxisomes. UBCH10 is useful for in vitro ubiquitinylation reactions.
Synonyms: Ubiquitin-conjugating enzyme E2 C, EC 6.3.2.19, Ubiquitin-protein ligase C, Ubiquitin carrier protein C, Ubc10, UBCH10, dJ447F3.2. - 分子量
- 21.1 kDa, a single non-glycosylated polypeptide chain containing 179 amino acids (a.a.) of human UBE2C/UBCH10 and 12 a.a. vector sequence including 6 x His tag at N-terminus.
- 途径
- Ubiquitin Proteasome Pathway
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