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Otoraplin Protein (OTOR) (AA 18-128)

OTOR 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analysis.
产品编号 ABIN2018309
发货至: 中国
  • 抗原 See all Otoraplin (OTOR) 蛋白
    Otoraplin (OTOR)
    蛋白类型
    Recombinant
    产品特性
    AA 18-128
    宿主
    • 2
    • 2
    • 1
    • 1
    资源
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    产品特性
    AA 18-128, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE analysis.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product OTOR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Otoraplin (rhOTOR) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhOTOR remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    Otoraplin (OTOR)
    Abstract
    OTOR 产品
    别名
    FDP Protein, MIAL1 Protein, CDRAP Protein, Fdp Protein, MIA Protein, MIAL Protein, MGC133655 Protein, MGC86203 Protein, otoraplin Protein, otoraplin L homeolog Protein, OTOR Protein, Otor Protein, otor.L Protein, otor Protein
    背景
    Otoraplin (OTOR) is a cytokine first identified in 2000 and encodes a small protein of 128 amino acids with an SH3 domain. OTOR is a homologue to CD-RAP/MIA and contains a hydrophobic N-terminal region as a signal peptide, which indicates that OTOR is mainly secreted. Researchers found that high expression of OTOR is only seen in the cochlea, demonstrating its importance in hearing. Indeed, loss of the gene produces cochlear dysfunction and otosclerosis, a hearing disorder involving the bony tissue of the ear. OTOR exerts an influence on the surrounding otic capsule and functions in the extracellular matrix of the membranous portion of the cochlea. Recombinant human Otoraplin (rhOTOR) produced in E. coli is a single non-glycosylated polypeptide chain containing 112 amino acids. rhOTOR has a molecular mass of 12.7 kDa analyzed by reducing SDS-PAGE.
    Synonyms: FDP, MIAL
    分子量
    12.7 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q9NRC9
    途径
    Sensory Perception of Sound, Regulation of Carbohydrate Metabolic Process
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