CCL8 Protein (AA 24-99)
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- 抗原 See all CCL8 蛋白
- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 24-99
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
- ED50< 0.5 xg/mL, measured by the FLIPR assay using CHO cells transfected with human CCR5, the receptor of human CCL8, corresponding to a specific activity of > 2 x 10^3 units/mg.
- 纯度
- > 95 % by SDS-PAGE analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product CCL8 蛋白
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Chemokine (C-C Motif) Ligand 8 (CCL8) (Active) protein
CCL8 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 8 (CCL8) (Active) proteinCCL8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) proteinCCL8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-97) protein (His tag)CCL8 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 8 (CCL8) (AA 24-99) protein (His tag)CCL8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 8 (CCL8) proteinCCL8 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human MCP-2/CCL8(rhMCP-2) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhMCP-2 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))
- 别名
- MCP-2/CCL8 (CCL8 产品)
- 别名
- HC14 Protein, MCP-2 Protein, MCP2 Protein, SCYA10 Protein, SCYA8 Protein, 1810063B20Rik Protein, AB023418 Protein, Mcp2 Protein, Scya8 Protein, C-C motif chemokine ligand 8 Protein, chemokine (C-C motif) ligand 8 Protein, C-C motif chemokine 8 Protein, monocyte chemoattractant protein-2 precursor Protein, CCL8 Protein, Ccl8 Protein, LOC101119572 Protein, MCP-2 Protein
- 背景
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MCP-2 is a member of the chemokines, a group of 70-80 residue proteins sharing substantial sequence similarity. Within the chemokines, MCP-2 belongs to the CC subfamily, and is a member of the Monocyte Chemoattractant Proteins (MCPs), which includes MCP-1, MCP-2, MCP-3, MCP-4, and MCP-5. MCP-2 shares 60 % homology with MCP-1, and both proteins can undergo reversible dimerization. The main receptors of MCP-2 are G-protein coupled receptors CCR1 and CCR5. MCP-2 is a potential target in HIV-1 infected human glial cells as it may play a role in the modulation of viral spread in the brain. Recently, researchers found that mouse MCP-2 is expressed in the skin as a novel agonist of CCR8 and plays a role in eosinophilic inflammation.Recombinant human MCP-2/CCL8(rhMCP-2) produced in E. coli is a single non-glycosylated polypeptide chain containing 76 amino acids. A fully biologically active molecule, rhMCP-2 has a molecular mass of 8.9 kDa analyzed by reducing SDS-PAGE.
Synonyms: Monocyte Chemoattractant Protein-2, HC14, SCYA8 - 分子量
- 8.9 kDa, observed by reducing SDS-PAGE.
- UniProt
- P80075
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