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M-CSF/CSF1 Protein (AA 33-187)

This Recombinant M-CSF/CSF1 protein is expressed in CHO Cells.
产品编号 ABIN2018209
发货至: 中国
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Quick Overview for M-CSF/CSF1 Protein (AA 33-187) (ABIN2018209)

抗原

See all M-CSF/CSF1 (CSF1) 蛋白
M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 34
  • 19
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  • 1
小鼠

资源

  • 23
  • 18
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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 33-187

    产品特性

    ED50< 3 ng/mL, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 3.3×10^5 units/mg.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant murine Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

    别名

    Macrophage Colony Stimulating Factor (M-CSF)

    背景

    Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers [1][3][4] .
    Synonyms: CSF1, CSF-1, MCSF

    分子量

    35-44 kDa, observed by non-reducing SDS-PAGE.

    UniProt

    Q3U4F9

    途径

    RTK signaling
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