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IL-5 Protein (AA 20-134)

This Recombinant IL-5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2018124
发货至: 中国

Quick Overview for IL-5 Protein (AA 20-134) (ABIN2018124)

抗原

See all IL-5 (IL5) 蛋白
IL-5 (IL5) (Interleukin 5 (IL5))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE.
  • 产品特性

    AA 20-134

    产品特性

    ED50 < 1.0 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 1.0x 10^6 units/mg.
    AA 20-134, expressed with an N-terminal Met.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against 25 mM Tris, pH 8.0.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Human Interleukin-5 (rhIL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    有效期

    6 months
  • 抗原

    IL-5 (IL5) (Interleukin 5 (IL5))

    别名

    Interleukin-5 (IL-5)

    背景

    Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Human Interleukin-5 (rhIL-5) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE.
    Synonyms: EDF, BCDFII, TRF

    分子量

    26.5 kDa, observed by non-reducing SDS-PAGE.

    UniProt

    P05113

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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