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IL-5 Protein (AA 20-134) (mFc Tag)

This Recombinant IL-5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7319796
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-5 Protein (AA 20-134) (mFc Tag) (ABIN7319796)

抗原

See all IL-5 (IL5) 蛋白
IL-5 (IL5) (Interleukin 5 (IL5))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 20-134

    标记

    This IL-5 protein is labelled with mFc Tag.

    原理

    Recombinant Human Interleukin-5/IL-5 (C-mFc)

    序列

    Ile20-Ser134

    产品特性

    Recombinant Human Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Ile20-Ser134 is expressed with a mFc tag at the C-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL-5 (IL5) (Interleukin 5 (IL5))

    别名

    Interleukin-5/IL-5

    背景

    Nterleukin,Interleukin,IL5,EDF,IL-5,TRF,BCDFII,B-cell differentiation factor I,B-cell growth factor I,BCGF-II,Cytotoxic T-lymphocyte inducer,E-CSF,Eosinophil differentiation factor,ESGF,Interleukin-5,nterleukin-5,T-cell replacing factor,IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.

    分子量

    Calculated MW: 39.8 kDa

    Observed MW: 40-55 kDa

    基因ID

    3567

    UniProt

    P05113

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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