IL1A Protein (AA 116-270)
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北京 101111
Quick Overview for IL1A Protein (AA 116-270) (ABIN2018082)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 116-270
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产品特性
- ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.
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有效期
- 6 months
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- Interleukin-1alpha (IL-1alpha)
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背景
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Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) -
分子量
- 17-22 kDa, observed by reducing SDS-PAGE.
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UniProt
- P16598
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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