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IL1A Protein (AA 116-270)

This Recombinant IL1A protein is expressed in CHO Cells.
产品编号 ABIN2018082
发货至: 中国
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Quick Overview for IL1A Protein (AA 116-270) (ABIN2018082)

抗原

See all IL1A 蛋白
IL1A (Interleukin 1 alpha (IL1A))

蛋白类型

Recombinant

生物活性

Active

宿主

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大鼠

资源

  • 43
  • 13
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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE.
  • 产品特性

    AA 116-270

    产品特性

    ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.

    有效期

    6 months
  • 抗原

    IL1A (Interleukin 1 alpha (IL1A))

    别名

    Interleukin-1alpha (IL-1alpha)

    背景

    Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
    Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

    分子量

    17-22 kDa, observed by reducing SDS-PAGE.

    UniProt

    P16598

    途径

    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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