IL1A 蛋白
Quick Overview for IL1A 蛋白 (ABIN2018030)
抗原
See all IL1A 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
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产品特性
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2 pg/mL, corresponding to a specific activity of > 5.0 x 10^8 IU/mg.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1 EU/μg of rMuIL-1μ as determined by LAL method.
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (Active) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 alpha (IL1A) (AA 115-270) (Active) protein (His tag)IL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- IL1A (Interleukin 1 alpha (IL1A))
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别名
- Interleukin-1 alpha
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背景
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Interleukin-1 alpha (IL-1a) is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1a and IL-1b binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1b is a secreted cytokine, IL-1a is predominantly a cell-associated cytokine.
Synonyms: Interleukin-1 Alpha, Mouse, -
分子量
- 17.9 kDa, a single non-glycosylated polypeptide chain containing 156 amino acids.
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途径
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
抗原
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