IL-5 Protein (AA 20-134)
Quick Overview for IL-5 Protein (AA 20-134) (ABIN2018023)
抗原
See all IL-5 (IL5) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 20-134
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产品特性
- ED50 < 1 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1x10^6 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant human Interlerkin 5 (rhIL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- IL-5 (IL5) (Interleukin 5 (IL5))
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别名
- Interleukin 5 (IL-5)
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背景
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Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Human IL-5 is homodimeric protein with molecular weight ranging from 29 to 35 kDa due to glycosylation.
Synonyms: EDF, BCDFII, TRF -
分子量
- -29-35 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P05113
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途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
抗原
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