IGF2 Protein (AA 25-91, Isoform 1)
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- 抗原 See all IGF2 蛋白
- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-91, Isoform 1
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
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ED50 < 20 ng/mL, measured by a cell proliferation assay using FDCP-1 cells, corresponding to a specific activity of > 5x10^4 units/mg.
AA 25-91 (isoform I), expressed with an N-terminal Met. - 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product IGF2 蛋白
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Insulin-Like Growth Factor 2 (IGF2) (AA 1-113) protein (GST tag)
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Insulin-Like Growth Factor 2 (IGF2) (AA 25-114) protein (GST tag)IGF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 (IGF2) (AA 1-180) protein (GST tag)IGF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) protein (His tag)Crystallography grade IGF2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor 2 (IGF2) (AA 26-91) protein (His tag)Crystallography grade IGF2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) protein (His tag)Crystallography grade IGF2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) (Active) protein (Fc Tag)IGF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Insulin-Like Growth Factor 2 (IGF2) (AA 30-180), (partial) protein (GST tag)IGF2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
Insulin-Like Growth Factor 2 (IGF2) (AA 25-91) (Active) protein (AVI tag,Fc Tag,Biotin)IGF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 25 mM Tris, pH 8.0.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Insulin-like Growth Factor II (rhIGF-II) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIGF-II remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
- 别名
- Insulin-Like Growth Factor II (IGF-II) (IGF2 产品)
- 别名
- C11orf43 Protein, IGF-II Protein, PP9974 Protein, LOC100136550 Protein, igf2 Protein, igf2b Protein, wu:fc26e03 Protein, zgc:91781 Protein, igf-2 Protein, insigf Protein, pp9974 Protein, AL033362 Protein, Igf-2 Protein, Igf-II Protein, M6pr Protein, Mpr Protein, Peg2 Protein, IGFII Protein, RNIGF2 Protein, IGF-II-B Protein, igf2-a Protein, igf2-b Protein, insulin like growth factor 2 Protein, insulin-like growth factor II Protein, insulin-like growth factor 2a Protein, insulin like growth factor 2 S homeolog Protein, insulin-like growth factor 2 Protein, insulin-like growth factor 2 (somatomedin A) Protein, insulin like growth factor 2 L homeolog Protein, IGF2 Protein, LOC100136550 Protein, igf2a Protein, igf2.S Protein, Igf2 Protein, igf2.L Protein
- 背景
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Insulin-like Growth Factor II (IGF-II) is a single chain 7 kDa polypeptide, and shares a high degree of homology with insulin. During circulation in vivo, IGF-II is complexed to high affinity binding proteins, IGF Binding Proteins (IGFBP), which act as circulating reservoirs, transport IGF-II, and prolong the half life of IGF-II. The receptors of IGF-II (IGFRs) are transmembrane tyrosine receptors, and are heterotetrameric consisting of two alpha-subunits and two beta-subunits. IGFRs execute their role via intracellullar signaling molecules, such as IRS, shc, and PI3K. The functions of IGF-II include promoting cell survival, growth, proliferation, differentiation and motility. In particular, IGF-II promotes proliferation, inhibits death, and stimulates transformation in breast cancer cells.Recombinant human Insulin-like Growth Factor II (rhIGF-II) produced in E. coli is a single non-glycosylated polypeptide chain containing 68 amino acids. A fully biologically active molecule, rhIGF-II has a molecular mass of 7.6 kDa analyzed by reducing SDS-PAGE.
Synonyms: Insulin-like Growth Factor-II, Somatamedin A - 分子量
- 7.6 kDa, observed by reducing SDS-PAGE.
- UniProt
- P01344
- 途径
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
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