GMFB Protein (AA 1-142)
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- 抗原 See all GMFB products
- GMFB (Glia Maturation Factor, beta (GMFB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-142
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 纯度
- > 95 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Glia Maturation Factor, beta (GMFB) (Active) protein
GMFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Glia Maturation Factor, beta (GMFB) (AA 1-142) protein (His tag)GMFB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glia Maturation Factor, beta (GMFB) (AA 1-154) protein (GST tag)GMFB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glia Maturation Factor, beta (GMFB) (AA 2-142) protein (His tag)Crystallography grade GMFB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Glia Maturation Factor beta (rhGMF-beta) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhGMF-beta remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- GMFB (Glia Maturation Factor, beta (GMFB))
- 别名
- Glia Maturation Factor beta (GMF-Beta) (GMFB 产品)
- 别名
- fc25b01 Protein, zgc:56451 Protein, zgc:86831 Protein, wu:fa97c03 Protein, wu:fc25b01 Protein, GMFB Protein, DKFZp459J101 Protein, gmfb Protein, 3110001H22Rik Protein, 3110001O16Rik Protein, AI851627 Protein, C79176 Protein, D14Ertd630e Protein, GMF Protein, gmf-beta Protein, glia maturation factor, beta Protein, glia maturation factor beta Protein, Glia maturation factor beta Protein, glia maturation factor, beta L homeolog Protein, gmfb Protein, GMFB Protein, Gmfb Protein, EDI_093190 Protein, Tsp_04922 Protein, LOC100101176 Protein, gmfb.L Protein
- 背景
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Glia Maturation Factor beta (GMF-beta) is a 17 kDa brain specific protein that belongs to the ADF/cofilin superfamily. It is a neurotrophin that induces maturation of neurons and glial cells, and. Unlike other neurotrophins, GMF-beta lacks a leader sequence and can be phosphorylated by protein kinase A and protein kinase C suggesting its role in signal transduction. GMF-beta is a prominent mediator of inflammation in the central nervous system and can activate several inflammation-related genes such as tumor necrosis factor-beta and interleukin-1beta. Researchers have shown there are significantly higher levels of GMF-beta protein in all the effected regions of Alzheimer's disease (AD) brains suggesting an important role of GMF-beta in AD pathogenesisRecombinant human Glia Maturation Factor beta (rhGMF-beta) produced in E. coli is a single non-glycosylated polypeptide chain containing 142 amino acids. rhGMF-beta has a molecular mass of 16.7 kDa analyzed by reducing SDS-PAGE.
Synonyms: GMFB - 分子量
- 16.7 kDa, observed by reducing SDS-PAGE.
- UniProt
- P60983
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