GDF10 Protein (AA 369-478)
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- 抗原 See all GDF10 蛋白
- GDF10 (Growth Differentiation Factor 10 (GDF10))
- 蛋白类型
- Recombinant
- 产品特性
- AA 369-478
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
- AA 369-478, expressed with an N-terminal Met.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product GDF10 蛋白
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Growth Differentiation Factor 10 (GDF10) (AA 379-478) protein (GST tag)
GDF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 10 (GDF10) (AA 1-288) protein (GST tag)GDF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 10 (GDF10) proteinGDF10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in 4 mM HCl at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 4 mM HCl.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Bone Morphogenetic Protein-3B (rhBMP-3B) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhBMP-3B remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- GDF10 (Growth Differentiation Factor 10 (GDF10))
- 别名
- Bone Morphogenetic Protein-3B (BMP-3B) (GDF10 产品)
- 别名
- GDF10 Protein, BMP-3b Protein, BMP3B Protein, Bmp3b Protein, bmp3b Protein, gdf-10 Protein, xBMP-3b Protein, growth differentiation factor 10 Protein, growth differentiation factor 10 L homeolog Protein, GDF10 Protein, Gdf10 Protein, gdf10.L Protein
- 背景
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Bone Morphogenetic Protein-3B (BMP-3B) , also known as Growth/Differentiation Factor 10 (GDF-10), is a cytokine belonging to the Transforming Growth Factor beta (TGF-beta) superfamily. BMP-3B contains the cystine knot motif shared by other TGF-beta family members. BMP-3B was originally identified by PCR based on the BMP-3 sequence, and shares 83 % identity with BMP-3. BMP-3B and BMP-2 act as mutual antagonists, as they compete for the availability of signaling protein Smad4. In vivo, BMP-3B is highly expressed in brain, lungs, and bone tissues. The functions of BMP-3B include acting as a dorsaling factor in head development, inhibition of adipogenesis in adipocytes, and induction of bone formation. BMP-3B is down-regulated in lung cancer patient samples, indicating its potential antitumor activity. Recombinant human Bone Morphogenetic Protein-3B (rhBMP-3B) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 111 amino acids each. rhBMP-3B has a molecular mass of 25.1 kDa analyzed by non-reducing SDS-PAGE.
Synonyms: Osteogenin, BMP-3A - 分子量
- 25.1 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P55107
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