TNFSF18 Protein (AA 74-198)
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- 抗原 See all TNFSF18 蛋白
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 74-198
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
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ED50 < 5 ng/mL, measured by the amount of Interleukin-8 produced by PMBC, corresponding to a specific activity of > 2.0 x 10^5 units/mg.
AA 74-198, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product TNFSF18 蛋白
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Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (His-DYKDDDDK Tag,Biotin)
TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (His-DYKDDDDK Tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (Fc Tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) protein (His tag)TNFSF18 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Active) proteinTNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 47-173) protein (Fc Tag)TNFSF18 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 50-177) protein (His-DYKDDDDK-Strep II Tag)TNFSF18 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 50-177) (Active) protein (His tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) proteinTNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 70-199) protein (His tag)TNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Activation-Inducible TNF-Related Ligand (rhAITRL) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhAITRL remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- 别名
- Activation-Inducible TNF-Related Ligand (AITRL) (TNFSF18 产品)
- 别名
- Gitrl Protein, AITRL Protein, GITRL Protein, TL6 Protein, hGITRL Protein, TNLG2A Protein, tumor necrosis factor (ligand) superfamily, member 18 Protein, TNF superfamily member 18 Protein, Tnfsf18 Protein, TNFSF18 Protein
- 背景
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Activation-Inducible TNF-Related Ligand (AITRL), also known as Glucocorticoid-Induced TNF-Related Ligand (GITRL), belongs to the tumor necrosis factor superfamily (TNFSF). AITRL is a Type II single transmembrane protein and shares low conservation within the extracellular domain with other TNFSF members. AITRL is expressed on macrophages, immature and mature dendritic cells and B cells. Its receptor, Activation-Inducible TNFR family Receptor (AITR), is expressed on T lymphocytes, natural killer (NK) cells, and antigen-presenting cells. Upon binding by AITRL, AITR can be released. AITR activation increases resistance to tumors and viral infections and is involved in autoimmune and inflammatory processes. In addition, activated AITR increases TCR-induced T cell proliferation and cytokine production and rescues T cells and NK cells from apoptosis. Recombinant human Activation-Inducible TNF-Related Ligand (rhAITRL) produced in E. coli is a single non-glycosylated polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhAITRL has a molecular mass of 14.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Activation-induced TNFR member Ligand, TNFSF18, GITRL, TL-6 - 分子量
- 14.3 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q9UNG2
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