CYP21A2 Protein (AA 1-495) (GST tag)
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- 抗原 See all CYP21A2 蛋白
- CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-495
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宿主
- 人
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资源
- 小麦胚
- 标记
- This CYP21A2 protein is labelled with GST tag.
- 应用范围
- Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)
- 原理
- CYP21A2 (Human) Recombinant Protein (P01)
- 序列
- MLLLGLLLLL PLLAGARLLW NWWKLRSLHL PPLAPGFLHL LQPDLPIYLL GLTQKFGPIY RLHLGLQDVV VLNSKRTIEE AMVKKWADFA GRPEPLTYKL VSRNYPDLSL GDYSLLWKAH KKLTRSALLL GIRDSMEPVV EQLTQEFCER MRAQPGTPVA IEEEFSLLTC SIICYLTFGD KIKDDNLMPA YYKCIQEVLK TWSHWSIQIV DVIPFLRFFP NPGLRRLKQA IEKRDHIVEM QLRQHKESLV AGQWRDMMDY MLQGVAQPSM EEGSGQLLEG HVHMAAVDLL IGGTETTANT LSWAVVFLLH HPEIQQRLQE ELDHELGPGA SSSRVPYKDR ARLPLLNATI AEVLRLRPVV PLALPHRTTR PSSISGYDIP EGTVIIPNLQ GAHLDETVWE RPHEFWPDRF LEPGKNSRAL AFGCGARVCL GEPLARLELF VVLTRLLQAF TLLPSGDALP SLQPLPHCSV ILKMQPFQVR LQPRGMGAHS PGQSQ
- 产品特性
- Human CYP21A2 full-length ORF (BAG37212.1, 1 a.a. - 495 a.a.) recombinant protein with GST tag at N-terminal.
- 纯化方法
- in vitro wheat germ expression system
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Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 1-487) protein (Strep Tag)
Crystallography grade CYP21A2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 1-494) protein (His tag)Crystallography grade CYP21A2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 2-261) protein (His tag)CYP21A2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 1-495), (full length) protein (His tag)CYP21A2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 2-261) protein (His-SUMO Tag)CYP21A2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (AA 2-261) protein (His tag)CYP21A2 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % SDS
Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CYP21A2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -80 °C
- 储存方法
- Best use within three months from the date of receipt of this protein.
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- 抗原
- CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
- 别名
- CYP21A2 (CYP21A2 产品)
- 别名
- CA21H Protein, CAH1 Protein, CPS1 Protein, CYP21 Protein, CYP21B Protein, P450c21B Protein, 21-OH Protein, 21OH Protein, 21OHA Protein, 21OHB Protein, CYP21OH-A Protein, Cyp21 Protein, Cyp21-ps1 Protein, Cyp21B Protein, Cyp21a2-ps Protein, Cyp21a2ps Protein, Oh21-1 Protein, Oh21-2 Protein, CYP21A Protein, 21-OHase Protein, cytochrome P450 family 21 subfamily A member 2 Protein, cytochrome P450, family 21, subfamily a, polypeptide 1 Protein, cytochrome P450c21 Protein, cytochrome P450, family 21, subfamily A, polypepide 2 Protein, cytochrome P450, family 21, subfamily A, polypeptide 2 Protein, steroid 21-hydroxylase-like Protein, CYP21A2 Protein, Cyp21a1 Protein, LOC101094596 Protein
- 背景
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Synonyms: CA21H,CAH1,CPS1,CYP21,CYP21B,MGC150536,MGC150537,P450c21B
Gene Description: cytochrome P450, family 21, subfamily A, polypeptide 2
Gene Name: CYP21A2
Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene, gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.
GenBank: AK314651.1, BAG37212.1 - 分子量
- 80.85 kDa (theoreatical)
- 基因ID
- 1589
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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