proBNP 蛋白
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- 抗原 See all proBNP products
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 纯度
- > 95 % by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS (pH 7.5)
- 储存液
- Without preservative
- 储存条件
- 4 °C
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- 抗原
- proBNP (Pro-Brain Natriuretic Peptide (proBNP))
- 别名
- Pro-BNP (proBNP 产品)
- 别名
- BNP Protein, natriuretic peptide B Protein, NPPB Protein
- 背景
- Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is released from the cardiac ventricles in response to increased wall tension. Rapid measurement of BNP is useful in establishing or excluding the diagnosis of congestive heart failure in patients with acute dyspnea. BNP is secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.
- 分子量
- 17 kDa
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