NGFB
宿主: 小鼠
宿主: 大肠杆菌(E. Coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute with sterile 18 mΩ/cm^3 H2O.
缓冲液
10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)
储存液
Without preservative
储存条件
4 °C
抗原
NGFB
(Nerve Growth Factor beta (NGFB))
别名
NGF beta
背景
Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.