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NGFB 蛋白

This Native NGFB protein is expressed in 小鼠.
产品编号 ABIN1880418
发货至: 中国

Quick Overview for NGFB 蛋白 (ABIN1880418)

抗原

See all NGFB 蛋白
NGFB (Nerve Growth Factor beta (NGFB))

蛋白类型

Native

生物活性

Active

宿主

  • 15
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

资源

  • 16
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
小鼠

纯度

> 95 % by SDS-PAGE
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with sterile 18 mΩ/cm^3 H2O.

    缓冲液

    10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

    储存液

    Without preservative

    储存条件

    4 °C
  • 抗原

    NGFB (Nerve Growth Factor beta (NGFB))

    别名

    NGF beta

    背景

    Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.

    分子量

    26.5 kDa

    途径

    NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
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