Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (AA 26-421) protein (His tag)
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- 抗原
- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
- 蛋白类型
- Recombinant
- 产品特性
- AA 26-421
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- His tag
- 原理
- Recombinant Human ACADM/MCAD (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MKANRQREPG LGFSFEFTEQ QKEFQATARK FAREEIIPVA AEYDKTGEYP VPLIRRAWEL GLMNTHIPEN CGGLGLGTFD ACLISEELAY GCTGVQTAIE GNSLGQMPII IAGNDQQKKK YLGRMTEEPL MCAYCVTEPG AGSDVAGIKT KAEKKGDEYI INGQKMWITN GGKANWYFLL ARSDPDPKAP ANKAFTGFIV EADTPGIQIG RKELNMGQRC SDTRGIVFED VKVPKENVLI GDGAGFKVAM GAFDKTRPVV AAGAVGLAQR ALDEATKYAL ERKTFGKLLV EHQAISFMLA EMAMKVELAR MSYQRAAWEV DSGRRNTYYA SIAKAFAGDI ANQLATDAVQ ILGGNGFNTE YPVEKLMRDA KIYQIYEGTS QIQRLIVARE HIDKYKN
- 产品特性
- Recombinant Human Medium-Chain Specific Acyl-CoA Dehydrogenase Mitochondrial/ACADM is produced with our E. coli expression system. The target protein is expressed with sequence (Lys26-Asn421) of Human ACADM fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (AA 26-421) protein (His tag)
宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (AA 1-100) protein (GST tag)宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (AA 1-421) protein (GST tag)宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, 20 % Glycerol, pH 8.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
- 别名
- ACADM
- 别名
- ACAD1 Protein, MCAD Protein, MCADH Protein, AU018656 Protein, acyl-CoA dehydrogenase medium chain Protein, acyl-Coenzyme A dehydrogenase, medium chain Protein, acyl-CoA dehydrogenase, C-4 to C-12 straight chain Protein, ACADM Protein, Acadm Protein
- Sub Type
- Fusionprotein
- 背景
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Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. ACADM is specific for acyl chain lengths of 4 to 16. It is essential for converting these particular fatty acids to energy, especially during fasting periods. Defects in ACADM cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.
Alternative Names: Medium-Chain Specific Acyl-CoA Dehydrogenase Mitochondrial, MCAD, ACADM - 分子量
- 45.9 kDa
- UniProt
- P11310
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