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BPGM Protein (AA 2-259) (His tag)

BPGM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1692049
发货至: 中国
  • 抗原 See all BPGM 蛋白
    BPGM (2,3-bisphosphoglycerate Mutase (BPGM))
    蛋白类型
    Recombinant
    产品特性
    AA 2-259
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This BPGM protein is labelled with His tag.
    原理
    Recombinant Human Bisphosphoglycerate Mutase/BPGM (C-6His)
    序列
    SKYKLIMLRH GEGAWNKENR FCSWVDQKLN SEGMEEARNC GKQLKALNFE FDLVFTSVLN RSIHTAWLIL EELGQEWVPV ESSWRLNERH YGALIGLNRE QMALNHGEEQ VRLWRRSYNV TPPPIEESHP YYQEIYNDRR YKVCDVPLDQ LPRSESLKDV LERLLPYWNE RIAPEVLRGK TILISAHGNS SRALLKHLEG ISDEDIINIT LPTGVPILLE LDENLRAVGP HQFLGDQEAI QAAIKKVEDQ GKVKQAKKLE HHHHHH
    产品特性
    Recombinant Human Bisphosphoglycerate Mutase/BPGM is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys259) of Human BPGM fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product BPGM 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0 .
    储存液
    Dithiothreitol (DTT)
    注意事项
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    BPGM (2,3-bisphosphoglycerate Mutase (BPGM))
    别名
    Bisphosphoglycerate Mutase/BPGM (BPGM 产品)
    别名
    DPGM Protein, AI323730 Protein, AL022789 Protein, C86192 Protein, Ab2-098 Protein, zgc:92230 Protein, Bisphosphoglycerate mutase Protein, bisphosphoglycerate mutase Protein, 2,3-bisphosphoglycerate mutase Protein, bisphosphoglycerate mutase S homeolog Protein, pmge Protein, BPGM Protein, Bpgm Protein, bpgm Protein, bpgm.S Protein
    Sub Type
    Fusionprotein
    背景
    Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
    Alternative Names: Bisphosphoglycerate Mutase, BPGM, 2,3-Bisphosphoglycerate Mutase Erythrocyte, 2,3-Bisphosphoglycerate Synthase, 2,3-Diphosphoglycerate Mutase, DPGM, BPG-Dependent PGAM, BPGM
    分子量
    31 kDa
    UniProt
    P07738
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