Recombinant Human T-Cell Receptor-Associated Transmembrane Adapter 1/TRAT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Asn29-Asn186) of Human TRAT1 fused with a 6His tag at the C-terminus.
纯度
> 95 % as determined by reducing SDS-PAGE.
过滤
0.2 μm filtered
内毒素水平
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
TRAT1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
限制
仅限研究用
状态
Liquid
溶解方式
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
缓冲液
Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,10 % Glycerol, pH 7.4.
注意事项
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
储存条件
-80 °C
储存方法
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
有效期
6 months
抗原
TRIM (TRAT1)
(T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
TCRIM Protein, TRIM Protein, C030046M14Rik Protein, Tcrim Protein, Trim Protein, T cell receptor associated transmembrane adaptor 1 Protein, T-cell receptor associated transmembrane adaptor 1 Protein, TRAT1 Protein, Trat1 Protein
Sub Type
Fusionprotein
背景
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. Alternative Names: T-Cell Receptor-Associated Transmembrane Adapter 1, T-Cell Receptor-Interacting Molecule, TRIM, pp29/30, TRAT1, TCRIM, HSPC062