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BMPR2 Protein (AA 27-151) (Fc Tag,His tag)

BMPR2 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1691570
发货至: 中国
  • 抗原 See all BMPR2 蛋白
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    蛋白类型
    Recombinant
    产品特性
    AA 27-151
    宿主
    • 15
    • 3
    资源
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This BMPR2 protein is labelled with Fc Tag,His tag.
    原理
    Recombinant Human BMP Receptor II/BMPR2/PPH1 (C-Fc-6His)
    序列
    SQNQERLCAF KDPYQQDLGI GESRISHENG TILCSKGSTC YGLWEKSKGD INLVKQGCWS HIGDPQECHY EECVVTTTPP SIQNGTYRFC CCSTDLCNVN FTENFPPPDT TPLSPPHSFN RDETIVDDIE GRMDEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSREEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH
    产品特性
    Recombinant Human Bone morphogenetic protein receptor type-2/BMPR2/PPH1 is produced by our mammalian expression system. The target protein is expressed with sequence (Ser27-Ile151) of Human BMPR- II fused with FC and polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product BMPR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    5 months
  • 抗原
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    别名
    BMPR II (BMPR2 产品)
    别名
    BMPR-II Protein, BMPR3 Protein, BMR2 Protein, BRK-3 Protein, PPH1 Protein, T-ALK Protein, 2610024H22Rik Protein, AL117858 Protein, AW546137 Protein, BB189135 Protein, BMP-2 Protein, BMPR-2 Protein, BMPRII Protein, Gm20272 Protein, Bmpr-II Protein, bmprii Protein, bone morphogenetic protein receptor type 2 Protein, bone morphogenetic protein receptor, type II b (serine/threonine kinase) Protein, bone morphogenetic protein receptor, type II (serine/threonine kinase) Protein, BMPR2 Protein, bmpr2b Protein, Bmpr2 Protein
    Sub Type
    Fusionprotein
    背景
    Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
    Alternative Names: Bone Morphogenetic Protein Receptor Type-2, BMP Type-2 Receptor, BMPR-2, Bone Morphogenetic Protein Receptor Type II, BMP Type II Receptor, BMPR-II, BMPR2, PPH1
    分子量
    41.9 kDa
    UniProt
    Q13873
    途径
    Growth Factor Binding
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