CDNF Protein (AA 25-187) (His tag)
CDNF
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- 抗原 See all CDNF 蛋白
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-187
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宿主
- 人
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资源
- 人细胞
- 标记
- This CDNF protein is labelled with His tag.
- 原理
- Recombinant Human Cerebral Dopamine Neurotrophic Factor/CDNF/ARMETL1 (C-6His)
- 序列
- QGQEAGGRPG ADCEVCKEFL NRFYKSLIDR GVNFSLDTIE KELISFCLDT KGKENRLCYY LGATKDAATK ILSEVTRPMS VHMPAMKICE KLKKLDSQIC ELKYEKTLDL ASVDLRKMRV AELKQILHSW GEECRACAEK TDYVNLIQEL APKYAATHPK TELHHHHHH
- 产品特性
- Recombinant Human Cerebral dopamine neurotrophic factor/CDNF is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln25Leu187) of Human CDNF fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CDNF 蛋白
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Cerebral Dopamine Neurotrophic Factor (CDNF) (AA 25-187) protein (His tag)
CDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cerebral Dopamine Neurotrophic Factor (CDNF) protein (His tag)CDNF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 5 months
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- 抗原
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- 别名
- CDNF (CDNF 产品)
- 别名
- ARMETL1 Protein, 9330140G23 Protein, Armetl1 Protein, cerebral dopamine neurotrophic factor Protein, CDNF Protein, Cdnf Protein
- Sub Type
- Fusionprotein
- 背景
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Erebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues.It is belongs to the ARMET family. CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
Alternative Names: Cerebral dopamine neurotrophic factor, ARMET-like protein 1, Conserved dopamine neurotrophic factor, ARMETL1 - 分子量
- 21.7 kDa
- UniProt
- Q49AH0
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