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- 抗原 See all HA2 products
- HA2 (H(+)-ATPase 2 (HA2))
- 蛋白类型
- Recombinant
- 宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HA2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS), Western Blotting (WB), Functional Studies (Func)
- 序列
- MGHHHHHHMA KWGQGDPRWI VEEREDGTNV NNWHWTERDA TIWSKGKLRE LLVGIAMENE AGRCEISELK QVEGEASCNS RKGKLIFFYE WNIKLAWKGT VKESGAKHKG LIEIPSLSEE NEINDTEVNV SKKKGDGEIL KDLMRTTGTA KVREALGEYL KALKTEFTTG MILPTKAVAT QELTLQRKLN ENKLQASPVA LGVRIPTVAL HLTELFDTTV EQLYSIFTVK ELVQKFSKSP AVLEAERGGK FQMFDGNISG EYVELVTNRK IIMKWRCRNW PEEHYATVEL NFVPAPGQTE LQLDCKGVPV CKEENMKFCW QKQHFEEIKG LLELTAQNA
- 特异性
- ~38 kDa
- 纯化方法
- Affinity Purified
- 纯度
- >90%
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H(+)-ATPase 2 (HA2) protein (His tag)
HA2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90% SDS, WB
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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This product has been certified >90% pure using SDS - PAGE analysis.
- 限制
- 仅限研究用
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- 浓度
- Lot specific
- 缓冲液
- 25 mM Trif buffer pH 7.2, 150 mM NaCl, 0.1 mM DTT, 50 % glycerol
- 储存条件
- -20 °C
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- 抗原
- HA2 (H(+)-ATPase 2 (HA2))
- 别名
- Aha2 (HA2 产品)
- 别名
- AHA2 Protein, F9N11.40 Protein, F9N11_40 Protein, H(+)-ATPase 2 Protein, P-TYPE H(+)-ATPASE ISOFORM 2 Protein, PLASMA MEMBRANE PROTON ATPASE 2 Protein, PMA2 Protein, H[+]-ATPase 2 Protein, HA2 Protein
- 背景
- Aha2 shares 45 % sequence homology with Aha1, however, little is known about the functional protein. Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
- 分子量
- approx. 38 kDa
- 基因ID
- 268390
- NCBI登录号
- NM_172391
- UniProt
- Q8N9S3
- 途径
- Cellular Glucan Metabolic Process, Proton Transport
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