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IL13 Receptor alpha 1 Protein (C-Term, Extracellular Domain)

IL13RA1 宿主: 人 宿主: HEK-293T Cells Recombinant > 98 %, as determined by SDS-PAGE and HPLC Active
产品编号 ABIN1684619
发货至: 中国
  • 抗原 See all IL13 Receptor alpha 1 (IL13RA1) 蛋白
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    C-Term, Extracellular Domain
    宿主
    • 16
    • 11
    • 1
    • 1
    资源
    • 14
    • 4
    • 4
    • 3
    • 2
    • 1
    HEK-293T Cells
    特异性
    Optimized DNA sequence encoding extracellular domain of human IL-13 receptor alpha 1 including a C terminal His tag and Fc tag was expressed in HEK293 cells.
    产品特性
    Recombinant IL-13RA1 is a homodimer protein consisting of two 570 amino acid residue subunits, due to glycosylation migrates as an approximately 90kDa protein on SDS-PAGE.
    纯度
    > 98 %, as determined by SDS-PAGE and HPLC
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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    Discover our top product IL13RA1 蛋白
  • 说明

    The activity was tested by immobilized recombinant human IL-13 (4 µg/mL) ability to bind recombinant human IL-13RA1 with a linear range of 0.1-2.5 µg/mL in functional ELISA.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS solution, pH7.2
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
    有效期
    12-24 months
  • 抗原
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    别名
    IL13RA1 (IL13RA1 产品)
    别名
    CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213A1 Protein, IL-13Ra Protein, NR4 Protein, AI882074 Protein, CD213a1 Protein, IL-13r[a] Protein, Il13ra Protein, IL13RA1 Protein, il-13ra1 Protein, si:ch211-150g2.2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 1 Protein, interleukin 13 receptor, alpha 1 Protein, interleukin 13 receptor, alpha 1-like Protein, IL13RA2 Protein, IL13RA1 Protein, Il13ra1 Protein, il13ra1 Protein, LOC100360218 Protein
    背景
    Thrombopoietin TPO, known also as TSF (thrombopoiesis stimulating factor), for mediator substances that function as natural stimulators of megakaryocytopoiesis and thus, promote the differentiation of platelets. TPO stimulates an increase in the sizes and numbers of megakaryocytes. It also increases the number of small acetyl-cholinesterase positive cells that are early precursor cells of the megakaryocytic lineage. TPO is a protein of 332 amino acids that shows significant homology with Epo (erythropoietin) in its N-terminal domain. A comparison of human and porcine TPO sequences shows 83 % identity between the erythropoietin-like domains but only 67 % between the C-terminal domains.
    UniProt
    P78552
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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