TNFSF18 Protein (AA 45-173, Extracellular Domain, Soluble) (DYKDDDDK Tag)
-
- 抗原 See all TNFSF18 蛋白
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Soluble, Extracellular Domain, AA 45-173
-
宿主
- 小鼠
-
资源
- HEK-293 Cells
- 标记
- This TNFSF18 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to mouse GITR.
- 交叉反应
- 小鼠
- 产品特性
- The extracellular domain of mouse GITRL (aa 45-173) is fused at the N-terminus to a FLAG®-tag.
- 纯度
- >90 % (SDS-PAGE)
- 过滤
- 0.2 μm filtered
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFSF18 蛋白
-
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (His-DYKDDDDK Tag,Biotin)
TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (His-DYKDDDDK Tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Trimer) protein (Fc Tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) protein (His tag)TNFSF18 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Active) proteinTNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 47-173) protein (Fc Tag)TNFSF18 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 50-177) protein (His-DYKDDDDK-Strep II Tag)TNFSF18 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 50-177) (Active) protein (His tag)TNFSF18 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) proteinTNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 70-199) protein (His tag)TNFSF18 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
Induces GITR-mediated NF-kappaB activation in HEK 293 cells.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- 0.2μm-filtered solution in 10 mM glycine, pH 10.0.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - 有效期
- 3 months
-
- 抗原
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- 别名
- GITRL (TNFSF18 产品)
- 别名
- Gitrl Protein, AITRL Protein, GITRL Protein, TL6 Protein, hGITRL Protein, TNLG2A Protein, tumor necrosis factor (ligand) superfamily, member 18 Protein, TNF superfamily member 18 Protein, Tnfsf18 Protein, TNFSF18 Protein
- 背景
- GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
- 分子量
- ~22kDa (SDS-PAGE)
- UniProt
- Q7TS55
-
